ddr inhibitor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10985	DDR Inhibitor		Discoidin Domain Receptor (DDR)
	DDR inhibitor is a potent discidin domain receptor (DDR) inhibitor. The IC50 of DDR2 is 3.3 nM, and DDR1 has 53% inhibition at 1.5 nM.		Discoidin Domain Receptor (DDR)
T3337	Ddr1-In-1		Discoidin Domain Receptor (DDR)
	DDR1-IN-1 is an effective and specific DDR1 receptor tyrosine kinase inhibitor (IC50: 105 nM), about 3-fold selectivity over DDR2.		Discoidin Domain Receptor (DDR)
T5402	DDR1-IN-2	DDR1 inhibitor 7rh	Discoidin Domain Receptor (DDR)
	DDR1-IN-2 (DDR1 inhibitor 7rh) (DDR1 inhibitor 7rh) is a potent, selective, ATP-competitive Discoidin domain receptor 1 (DDR1) inhibitor (IC50: 6.8 nM in cell-free kinase assays).		Discoidin Domain Receptor (DDR)
T70201	S 16020-2
	S 16020-2 is an olivacine derivative, and DNA topoisomerase II inhibitor endowed with a remarkable antitumor activity against various experimental tumors.
T10984	DDR-TRK-1		Discoidin Domain Receptor (DDR)
	DDR-TRK-1 is a selective discoid domain receptor 1 (DDR1) inhibitor with IC50 value of 9.4 nM. DDR-TRK-1 also inhibits the TRK family.		Discoidin Domain Receptor (DDR)
T78959	ATR-IN-23		ATM/ATR
	ATR-IN-23 (Compound 34), a potent and selective ATR inhibitor, exhibits an IC50 of 1.5 nM, has demonstrated antiproliferative effects on LoVo cells, and induces synthetic lethality in HT-29 cells, suggesting its utility ...		ATM/ATR
T62651	ATR-IN-11
	ATR-IN-11 (Compound Hit01) is a potent inhibitor of ataxia capillaris and Rad3-related (ATR) kinases. ATR-IN-11 is a promising lead compound for the discovery of subsequent drugs targeting the ATR kinase, a key regulator...